Our recent work has revealed two distinct approaches for controlling the bundling of actin filaments:
Importance of Achievement:
Alignment of semi-rigid actin filaments to form bundles is a key step toward creating rigid structural elements that can withstand and apply tunable mechanical forces in actin-based materials.
Relationship of Achievement to IRG:
Now that we can control filament bundling, we are engineering fuel-driven bundling, a key step toward out-of-equilibrium actin-based materials.