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Mussel protein adhesion to mica surpasses biotin-avidin affinity

Asymmetrical films of adhesive protein Mfp-5 show significantly higher reversible adhesion to smooth mica surfaces than the “gold standard” of noncovalent binding: well-ordered avidin-biotin interactions. The insights are crucial for intelligent translation of mussel adhesion to engineered systems.

conditions were pH 3, ionic strength 0.15 M at ambient temperature and pressure