New materials are typically created using the most basic building blocks of matter - atoms of the different elements in the periodic table. The Center for Precision Assembly of Superstratic and Superatomic Solids -- led by Columbia University in partnership with City College of New York, Harvard University, Barnard College, and the University of the Virgin Islands -- seeks to create novel materials from two new types of building blocks: atomically thin sheets stacked into layered structures; and precisely defined clusters of atoms linked together into bulk solids. The Center research will provide better understanding of low-dimensional materials and their interactions. This understanding will aid in the design and discovery of new materials with better applications in electronic/magnetic devices, optoelectronic systems, and thermoelectrics. The Center provides interdisciplinary graduate research training and opportunities for undergraduate research; includes research partners in industry, national laboratories, and internationally; and will build new shared instrumentation facilities available to the research community. The Center includes a comprehensive program to improve and support science education through partnerships with three local K-12 schools, and a new pilot program at the Columbia School of Journalism.